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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 553105Generated: October 25, 2026

(2S)-2-hydroxy-3,3-dimethylbutanoic acid → HCID 11646322, compound

https://huagongshe.com/reaction/553105

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-2-hydroxy-3,3-dimethylbutanoic acidHCID 11097105—
Reactant2-Amino-pentanoic acid [1-(1-ethyl-propyl)-1H-imidazol-4-yl]-amideHCID 67165041—
ProductHCID 11646322HCID 11646322—

Reaction Steps

2-Amino-pentanoic acid [1-(1-ethyl-propyl)-1H-imidazol-4-yl]-amide was coupled with (S)-2-hydroxy-3,3-dimethyl-butyric acid to provide the title compound: C13 NMR (100 MHz, CDCl3) 10.8, 13.9, 19.0, 26.3, 28.8, 35.3, 35.6, 52.7, 62.9, 79.8, 104.8, 132.7, 137.9, 169.2, 172.9; MS 367.1 m/z (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07951958B2
Source datasetuspto-grants-2011_05
ORD IDord-4740043f1de947a2ae8177712c92288b
Source noteuspto-grants-2011_05