HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-Hydroxy-3-methylbutanoic acid → 2-(2-Hydroxy-3-methyl-butyrylamino)-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-Hydroxy-3-methylbutanoic acid | HCID 853180 | — |
| Reactant | 2-Amino-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amide | HCID 67164226 | — |
| Product | 2-(2-Hydroxy-3-methyl-butyrylamino)-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amide | HCID 11654395 | — |
Reaction Steps
2-Amino-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amide was coupled with (S)-2-hydroxy-3-methyl-butyric acid to afford the title compound:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951958B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-e9560074fc5d400c99cfb06a49af15db |
| Source note | uspto-grants-2011_05 |