Morpholine → HCID 67163299, compound

HRID 553141Notes

Reaction equation

HRID 553141 reaction equation
[CH3:1][C:2]([N:7]1[CH:11]=[C:10]([NH:12][C:13](=[O:30])[CH:14]([NH:18][C:19](=[O:29])[CH2:20][C:21]2[CH:26]=[C:25]([F:27])[CH:24]=[C:23]([F:28])[CH:22]=2)[CH2:15][CH2:16][CH3:17])[N:9]=[CH:8]1)([CH3:6])[CH2:3][CH:4]=O.[NH:31]1[CH2:36][CH2:35][O:34][CH2:33][CH2:32]1>>[CH3:1][C:2]([N:7]1[CH:11]=[C:10]([NH:12][C:13](=[O:30])[CH:14]([NH:18][C:19](=[O:29])[CH2:20][C:21]2[CH:22]=[C:23]([F:28])[CH:24]=[C:25]([F:27])[CH:26]=2)[CH2:15][CH2:16][CH3:17])[N:9]=[CH:8]1)([CH3:6])[CH2:3][CH2:4][N:31]1[CH2:36][CH2:35][O:34][CH2:33][CH2:32]1

Participants

3

Reactant 2

HCID 8083MorpholineHCID 86600812HCID 86600812, compound

Product 1

HCID 67163299HCID 67163299, compound

Procedure

2-[2-(3,5-Difluoro-phenyl)-acetylamino]-pentanoic acid [1-(1,1-dimethyl-3-oxo-propyl)-1H-imidazol-4-yl]-amide was reacted with morpholine to afford the title compound: MS m/z 492.2 (M+1).

Sources & evidence

ORD record
ord-930378909ade49df9a65b5604ea64dff
Source dataset
uspto-grants-2011_05
Patent number
US07951958B2

Reaction notes

Loading…