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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 553165Generated: November 2, 2026

2-Amino-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amide → HCID 11627479, compound

https://huagongshe.com/reaction/553165

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amideHCID 67164226—
ReactantHCID 67165381HCID 67165381—
ProductHCID 11627479HCID 11627479—

Reaction Steps

2-Amino-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amide was reacted with 6,8-Difluoro-1,1-dimethyl-3,4-dihydro-1H-naphthalen-2-one to afford the title compound: C13 NMR (100 MHz, CDCl3) 14.3, 19.4, 19.7, 22.5, 23.0, 24.3, 24.8, 26.3, 26.6, 27.4, 27.5, 29.7, 36.4, 37.1, 38.0, 45.8, 47.6, 56.0, 59.2, 60.7, 62.5, 63.0, 65.5, 67.3, 104.7, 104.8, 111.0, 110.2, 112.5, 131.1, 131.2, 137.2, 172.2; MS m/z 502.3. (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07951958B2
Source datasetuspto-grants-2011_05
ORD IDord-474bbb214c6e4c3389c2ace57206580f
Source noteuspto-grants-2011_05