Lithium borohydride → HCID 67165345, compound

Participants

Reaction Steps

2M Lithium borohydride in tetrahydrofuran solution (0.7 mL) was added to a solution of (3-{2-[tert-butoxycarbonyl-(2-methoxy-ethyl)-amino]-ethyl}-phenyl)-acetic acid ethyl ester (230 mg) in tetrahydrofuran (10 mL) and heated to reflux for 1 hour. On cooling, the reaction was diluted with ethyl acetate and extracted sequentially, twice with saturated aqueous sodium bicarbonate solution, once with brine, dried over magnesium sulfate and evaporated, to give the subtitle compound as an oil (200 mg).

Provenance & Evidence