HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Phenylenediacetic acid → HCID 67166004, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Phenylenediacetic acid | HCID 29788 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | 2-Methoxybenzylamine | HCID 81292 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Product | HCID 67166004 | HCID 67166004 | 31% |
Reaction Steps
Prepared from 2-methoxy-benzylamine (1.4 g), (3-carboxymethyl-phenyl)-acetic acid (2 g), 1-hydroxybenzotriazole (1.4 g), Hunigs base (1.8 mL), 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (2.0 g), using the method of Example 44 (step a), to give 990 mg of the sub-titled compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951954B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-3992b8cb610b4e719e11e291d02df082 |
| Source note | uspto-grants-2011_05 |