HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azepane → HCID 67165265, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azepane | HCID 8119 | — |
| Reactant | m-Phenylenediacetic acid | HCID 29788 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Product | HCID 67165265 | HCID 67165265 | 49.9% |
Reaction Steps
Prepared from (3-carboxymethyl-phenyl)-acetic acid (990 mg), azepane (500 g), 1-hydroxybenzotriazole (690 mg), Hunigs base (0.89 mL), 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (980 mg), using the method of Example 44 (step a), to give 700 mg of the sub-titled compound as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07951954B2 |
| Source dataset | uspto-grants-2011_05 |
| ORD ID | ord-470cbd05041f4b0eb0888922cc341f19 |
| Source note | uspto-grants-2011_05 |