HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acryloyl chloride → [2-(Acryloylamino)phenyl]boronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acryloyl chloride | HCID 13140 | — |
| Reactant | (2-Aminophenyl)boronic acid | HCID 2773216 | — |
| Product | [2-(Acryloylamino)phenyl]boronic acid | HCID 18997948 | — |
Reaction Steps
2-Acrylamido-phenylboronic acid (“2-APB”) was synthesized by reacting 2-aminophenylboronic acid with an excess of acryloyl chloride in an aqueous alkaline solution. The product was extracted in acetone and dried using a rotary evaporator. The structure of 2-APB was confirmed using NMR. The purity was shown to be greater than 90%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08048680B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-c83f9a78c34a455c8b29550583c48eaa |
| Source note | uspto-grants-2011_11 |