Phosphorus oxychloride → Ethyl (chlorosulfonyl)acetate

Participants

Reaction Conditions

Reaction Steps

A mixture of (ethoxycarbonyl)methanesulfonic acid (10 g, 60 mmol.) and POCl3 (45 mL) was heated at 125° C. for 5 h. The mixture was cooled and filtered, and excess POCl3 was removed to give crude (ethoxycarbonyl)methanesulfonyl chloride (8.1 g, 80%) used directly without purification.

Provenance & Evidence