Trifluoroacetic acid → HCID 57671528, compound

Participants

Reaction Steps

The title compound was prepared similarly to the procedure described for Example 1 (g) by treatment of tert-butyl 2-(6-cyclohexenyl-4-hydroxy-1-methyl-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamido)acetate (Example 66 (a)) with TFA. MS (ESI, pos. ion) m/z: 357 (M+1). 1H NMR (300 MHz, DMSO-d6) δ ppm: 10.48 (t, J=5.6 Hz, 1 H), 8.93 (d, J=2.3 Hz, 1 H), 8.28 (d, J=1.9 Hz, 1 H), 6.39 (br. s, 1 H), 4.13 (d, J=5.6 Hz, 2 H), 3.69 (s, 3 H), 2.39-2.46 (m, 2 H), 2.17-2.27 (m, 2 H), 1.70-1.84 (m, 2 H), 1.59-1.69 (m, 2 H).

Provenance & Evidence