Trifluoroacetic acid → HCID 57671600, compound

Participants

Reaction Steps

The title compound was prepared similarly to the procedure described for Example 1 (g) by treatment of tert-butyl 2-(6-ethynyl-4-hydroxy-1-methyl-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamido)acetate (Example 79 (b)) with TFA. MS (ESI, pos. ion) m/z: 302 (M+1). 1H NMR (300 MHz, DMSO-d6) δ ppm: 10.39 (t, J=5.3 Hz, 1 H), 8.91 (d, J=2.2 Hz, 1 H), 8.44 (d, J=2.3 Hz, 1 H), 4.51 (s, 1 H), 4.15 (d, J=5.7 Hz, 2 H), 3.68 (s, 3 H).

Provenance & Evidence