Trifluoroacetic acid → HCID 57671566, compound

Participants

Reaction Steps

The title compound was prepared similarly to the procedure described for Example 1 (g) by treatment of tert-butyl 2-(6-(2-cyclopropylethynyl)-4-hydroxy-1-methyl-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamido)acetate (Example 81 (a)) with TFA. MS (ESI, pos. ion) m/z: 342 (M+1). 1H NMR (300 MHz, DMSO-d6) δ ppm: 10.40 (t, J=5.6 Hz, 1 H), 8.80 (d, J=2.2 Hz, 1 H), 8.31 (d, J=2.2 Hz, 1 H), 4.14 (d, J=5.6 Hz, 2 H), 3.67 (s, 3 H), 1.53-1.67 (m, 1 H), 0.86-0.99 (m, 2 H), 0.74-0.87 (m, 2 H).

Provenance & Evidence