HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 57671478, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 57671692 | HCID 57671692 | — |
| Product | HCID 57671478 | HCID 57671478 | — |
Reaction Steps
The title compound was prepared similarly to the procedure described for Example 1 (g) by treatment of tert-butyl 2-(6-bromo-4-hydroxy-1-methyl-2-oxo-7-(trifluoromethyl)-1,2-dihydro-1,8-naphthyridine-3-carboxamido)acetate (Example 90 (d)) with TFA. MS (ESI, pos. ion) m/z: 425 (M+1). 1H NMR (300 MHz, DMSO-d6) δ ppm: 13.02 (br. s, 1 H), 10.34 (s, 1 H), 8.81 (s, 1 H), 4.16 (d, J=5.7 Hz, 2 H), 3.65 (s, 3 H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08048892B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-b109a32973db48f990a828d91fe027a4 |
| Source note | uspto-grants-2011_11 |