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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 553528Generated: October 30, 2026

Trifluoroacetic acid → HCID 57671478, compound

https://huagongshe.com/reaction/553528

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 57671692HCID 57671692—
ProductHCID 57671478HCID 57671478—

Reaction Steps

The title compound was prepared similarly to the procedure described for Example 1 (g) by treatment of tert-butyl 2-(6-bromo-4-hydroxy-1-methyl-2-oxo-7-(trifluoromethyl)-1,2-dihydro-1,8-naphthyridine-3-carboxamido)acetate (Example 90 (d)) with TFA. MS (ESI, pos. ion) m/z: 425 (M+1). 1H NMR (300 MHz, DMSO-d6) δ ppm: 13.02 (br. s, 1 H), 10.34 (s, 1 H), 8.81 (s, 1 H), 4.16 (d, J=5.7 Hz, 2 H), 3.65 (s, 3 H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08048892B2
Source datasetuspto-grants-2011_11
ORD IDord-b109a32973db48f990a828d91fe027a4
Source noteuspto-grants-2011_11