Trifluoroacetic acid → HCID 57671610, compound

Participants

Reaction Steps

The title compound was prepared similarly to the procedure described for Example 1 (g) by treatment of tert-butyl 2-(6-cyclohexenyl-4-hydroxy-1-methyl-2-oxo-7-(trifluoromethyl)-1,2-dihydro-1,8-naphthyridine-3-carboxamido)acetate (Example 95 (a)) with TFA. MS (ESI, pos. ion) m/z: 426 (M+1). 1H NMR (300 MHz, DMSO-d6) δ ppm: 13.02 (s, 1 H), 10.39 (t, J=5.6 Hz, 1 H), 8.35 (s, 1 H), 5.52-5.79 (m, 1 H), 4.15 (d, J=5.6 Hz, 2 H), 3.66 (s, 3 H), 2.04-2.37 (m, 4 H), 1.57-1.89 (m, 4 H).

Provenance & Evidence