HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → 5-(4-Bromo-3-methyl-phenyl)-3-methyl-isoxazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | 5-(4-Bromo-3-methyl-phenyl)-3-methyl-isoxazole-4-carboxylic acid methyl ester | HCID 58539693 | — |
| Product | 5-(4-Bromo-3-methyl-phenyl)-3-methyl-isoxazole-4-carboxylic acid | HCID 58539445 | — |
Reaction Steps
5-(4-Bromo-3-methyl-phenyl)-3-methyl-isoxazole-4-carboxylic acid methyl ester (7.26 g, 23.4 mmol) was hydrolyzed with 1N aqueous LiOH. Acidic work-up provided the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08048902B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-940db2daf7074a998e8145dd6fd4eb1e |
| Source note | uspto-grants-2011_11 |