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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 553717Generated: October 25, 2026

o-Fluoroacetophenone → (1S)-1-(2-Fluorophenyl)ethan-1-ol

https://huagongshe.com/reaction/553717

Reaction equation

Participants

RoleNameHCIDCharge
Reactanto-FluoroacetophenoneHCID 96744—
Reactant(R)-2-Methyl-CBS-oxazaborolidineHCID 9838490—
Product(1S)-1-(2-Fluorophenyl)ethan-1-olHCID 7023576—

Reaction Steps

(S)-1-(2-Fluoro-phenyl)-ethanol was prepared according to the procedure described in Example 35, Step 1 using 2′-fluoroacetophenone and (R)-(+)-2-methyl-CBS-oxazaborolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08048902B2
Source datasetuspto-grants-2011_11
ORD IDord-9cbd29eeb76e4f53b20d0ecd8592f9e7
Source noteuspto-grants-2011_11