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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 553747Generated: November 1, 2026

3-Hydroxyacetophenone → (R)-3-(1-HYDROXYPROPYL)PHENOL

https://huagongshe.com/reaction/553747

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-HydroxyacetophenoneHCID 8487—
Reactant(3aS)-1-methyl-3,3-diphenyl-hexahydropyrrolo(1,2-c)(1,3,2)oxazaboroleHCID 2734713—
Product(R)-3-(1-HYDROXYPROPYL)PHENOLHCID 13542887—

Reaction Steps

3′-hydroxyacetophenone and (S)-(−)-2-methyl-CBS-oxazaborolidine were reacted as described in Example 35, Step 1 to provide 3-((R)-1-hydroxy-ethyl)-phenol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08048902B2
Source datasetuspto-grants-2011_11
ORD IDord-73aa3c0f91d84130854f97307bbf1493
Source noteuspto-grants-2011_11