HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Methoxypyridine → 1-(4-bromobutyryl)-2-(3,4,5-trifluorophenyl)-2,3-dihydro-1H-pyridin-4-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Methoxypyridine | HCID 69278 | — |
| Edukt | 4-Bromobutyryl chloride | HCID 70225 | — |
| Edukt | HCID 178505944 | HCID 178505944 | — |
| Produkt | 1-(4-bromobutyryl)-2-(3,4,5-trifluorophenyl)-2,3-dihydro-1H-pyridin-4-one | HCID 67462884 | — |
Reaktionsschritte
1.02 g of the title compound was obtained from 4-methoxypyridine (1.52 mL), 3,4,5-trifluorophenylmagnesium bromide (0.3 M solution in THF, 50 mL), and 4-bromobutyryl chloride (1.74 mL) according to the method described in Tetrahedron Letters, 1986, vol. 27, p. 4549-4552. The property values of the compound are as follows.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08048878B2 |
| Quelldatensatz | uspto-grants-2011_11 |
| ORD ID | ord-5d7987821a004c919b8153d5c4ce14f9 |
| Quellennotiz | uspto-grants-2011_11 |