Zurück
HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 553865Erstellt: 26. Oktober 2026

4-Methoxypyridine → 1-(4-bromobutyryl)-2-(3,4,5-trifluorophenyl)-2,3-dihydro-1H-pyridin-4-one

https://huagongshe.com/reaction/553865

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt4-MethoxypyridineHCID 69278—
Edukt4-Bromobutyryl chlorideHCID 70225—
EduktHCID 178505944HCID 178505944—
Produkt1-(4-bromobutyryl)-2-(3,4,5-trifluorophenyl)-2,3-dihydro-1H-pyridin-4-oneHCID 67462884—

Reaktionsschritte

1.02 g of the title compound was obtained from 4-methoxypyridine (1.52 mL), 3,4,5-trifluorophenylmagnesium bromide (0.3 M solution in THF, 50 mL), and 4-bromobutyryl chloride (1.74 mL) according to the method described in Tetrahedron Letters, 1986, vol. 27, p. 4549-4552. The property values of the compound are as follows.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08048878B2
Quelldatensatzuspto-grants-2011_11
ORD IDord-5d7987821a004c919b8153d5c4ce14f9
Quellennotizuspto-grants-2011_11