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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 553879Generated: October 30, 2026

(6R*,9aS*)-6-(4-methoxyphenyl)-3,6,7,8,9,9a-hexahydroquinolizin-4-one → (6R*,9aS*)-6-(4-methoxyphenyl)octahydroquinolizin-4-one

https://huagongshe.com/reaction/553879

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(6R*,9aS*)-6-(4-methoxyphenyl)-3,6,7,8,9,9a-hexahydroquinolizin-4-oneHCID 69072392—
ReactantHCID 178418361HCID 178418361—
CatalystPlatinum oxide (PtO)HCID 82844—
SolventMethanolHCID 887—
Product(6R*,9aS*)-6-(4-methoxyphenyl)octahydroquinolizin-4-oneHCID 6907086781.5%

Reaction Steps

Platinum oxide (2 mg) was added to a solution of (6R*,9aS*)-6-(4-methoxyphenyl)-3,6,7,8,9,9a-hexahydroquinolizin-4-one (28 mg) in methanol (5 mL), and the reaction solution was stirred in a hydrogen stream at room temperature for 13 hours. The reaction solution was filtered through celite, and the filtrate was concentrated under reduced pressure to obtain 23 mg of the title compound. The property values of the compound are as follows.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08048878B2
Source datasetuspto-grants-2011_11
ORD IDord-962f1dadef664bf0a55ec32702bb57ad
Source noteuspto-grants-2011_11