HCID 67463325, compound → HCID 67460827, compound

Participants

Reaction Steps

Platinum oxide (162 mg) was added to a solution of (6S,9aR)-6-(3,4,5-trifluorophenyl)-3,6,7,8,9,9a-hexahydroquinolizin-4-one (2.01 g) in methanol (50 mL), and the reaction solution was stirred in a hydrogen stream at room temperature for seven hours. The reaction solution was filtered through celite, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (elution solvent: heptane-ethyl acetate system) to obtain 1.79 g of the title compound. The property value of the compound is as follows.

Provenance & Evidence