HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-[(2,4-dichlorophenyl)methyl]-1,3,3-trimethyl-5-oxoprolinamide → N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-1,3,3-trimethyl-5-oxoprolinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-[(2,4-dichlorophenyl)methyl]-1,3,3-trimethyl-5-oxoprolinamide | HCID 67460084 | — |
| Reactant | [2-Chloro-3-(trifluoromethyl)phenyl]methyl isocyanide | HCID 86617532 | — |
| Product | N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-1,3,3-trimethyl-5-oxoprolinamide | HCID 67458667 | — |
Reaction Steps
N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-1,3,3-trimethyl-5-oxoprolinamide was prepared in a manner analogous to that described above for the synthesis of N-[(2,4-dichlorophenyl)methyl]-1,3,3-trimethyl-5-oxoprolinamide (E127) but using [2-chloro-3-(trifluoromethyl)phenyl]methyl isocyanide (prepared as described in example 40) in the place of (2,4-dichlorophenyl)methyl isocyanide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08048907B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-810295b11fca41f18b5e60c558d12647 |
| Source note | uspto-grants-2011_11 |