Benzenesulfonyl chloride → HCID 86232862, compound

HRID 554182Notes

Reaction equation

HRID 554182 reaction equation
CC1NC(C2C=CC=CC=2)=CC=1C(OCC)=O.C1(S(Cl)(=O)=O)C=CC=CC=1.[CH3:28][C:29]1[N:30]([S:45]([C:48]2[CH:53]=[CH:52][CH:51]=[CH:50][CH:49]=2)(=[O:47])=[O:46])[C:31]([C:39]2[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=2)=[CH:32][C:33]=1[C:34](OCC)=[O:35]>>[CH3:28][C:29]1[N:30]([S:45]([C:48]2[CH:53]=[CH:52][CH:51]=[CH:50][CH:49]=2)(=[O:47])=[O:46])[C:31]([C:39]2[CH:40]=[CH:41][CH:42]=[CH:43][CH:44]=2)=[CH:32][C:33]=1[CH:34]=[O:35]

Participants

4

Reactant 3

HCID 7369Benzenesulfonyl chlorideHCID 12258777Ethyl 2-methyl-5-phenyl-1H-pyrrole-3-carboxylateHCID 66924632Ethyl 2-methyl-5-phenyl-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate

Product 1

HCID 86232862HCID 86232862, compound

Procedure

Using ethyl 2-methyl-5-phenyl-1H-pyrrole-3-carboxylate and benzenesulfonyl chloride, a procedure as in Reference Example 4 was performed to synthesize ethyl 2-methyl-5-phenyl-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate, and procedures as in Reference Examples 5 and 6 were sequentially performed to give the title compound as a colorless oil.

Sources & evidence

ORD record
ord-a54d767365ac456bbeebdffd79ca7a3b
Source dataset
uspto-grants-2011_11
Patent number
US08048909B2

Reaction notes

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