HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 66925099, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 4-Fluorophenylboronic acid | HCID 285645 | — |
| Reactant | HCID 66924863 | HCID 66924863 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Product | HCID 66925099 | HCID 66925099 | 90.1% |
Reaction Steps
Using tert-butyl {{5-bromo-1-[(3-chlorophenyl)sulfonyl]-1H-pyrrol-3-yl}methyl}methylcarbamate (1 g), (4-fluorophenyl)boronic acid (628 mg), sodium carbonate (708 mg) and tetrakis(triphenylphosphine)palladium (388 mg), a procedure as in Reference Example 56 was performed to give the title compound as a pale-yellow oil (yield 930 mg, 87%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08048909B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-d6989d62a3b64874a1c48a8586fabac2 |
| Source note | uspto-grants-2011_11 |