N-bromobutanimide → HCID 66924684, compound

HRID 554234Notes

Reaction equation

HRID 554234 reaction equation
[CH:1]([C:4]1[C:5]([C:9]([O:11][CH3:12])=[O:10])=[CH:6][NH:7][CH:8]=1)([CH3:3])[CH3:2].[Br:13]N1C(=O)CCC1=O>N1C=CC=CC=1>[Br:13][C:8]1[NH:7][CH:6]=[C:5]([C:9]([O:11][CH3:12])=[O:10])[C:4]=1[CH:1]([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 67184N-bromobutanimideHCID 66924650HCID 66924650, compound

Product 1

HCID 66924684HCID 66924684, compoundYield 64%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Using methyl 4-isopropyl-1H-pyrrole-3-carboxylate (3.5 g), N-bromosuccinimide (3.74 g) and pyridine (0.5 mL), a procedure as in Reference Example 40 was performed to give the title compound as colorless crystals (yield 3.29 g, 64%).

Sources & evidence

ORD record
ord-1066d0002c7644b4aaccbaeaabaf2a9e
Source dataset
uspto-grants-2011_11
Patent number
US08048909B2

Reaction notes

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