Methyl morpholine oxide → HCID 86620751, compound

Participants

Reaction Steps

Using ethyl 4-chloro-2-methyl-5-phenyl-1-(phenylsulfonyl)-1H-pyrrole-3-carboxylate (610 mg), a 1.5 mol/L solution (6.0 mL) of diisobutylaluminum hydride in toluene, tetra-n-propylammonium perruthenate (53 mg), N-methylmorpholine N-oxide (195 mg) and molecular sieves 4A powder (300 mg), a procedure as in Reference Example 49 was performed to give the title compound as a pale-yellow solid (yield 301 mg, 55%).

Provenance & Evidence