HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 86232840, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 15-Crown-5 | HCID 36336 | — |
| Reactant | 1,3-Benzothiazole-6-sulfonyl chloride | HCID 2795170 | — |
| Reactant | 5-Phenyl-1H-pyrrole-3-carboxaldehyde | HCID 11052090 | — |
| Product | HCID 86232840 | HCID 86232840 | 85.4% |
Reaction Steps
Using 5-phenyl-1H-pyrrole-3-carbaldehyde (135 mg), sodium hydride (60% in oil, 38.3 mg), 15-crown-5 (0.18 mL) and 6-benzothiazolesulfonyl chloride (206 mg), a procedure as in Reference Example 219 was performed to give the title compound as white crystal (yield 248 mg, 85%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08048909B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-09c66b30e0f745f0bdcc8198a5dc1a1e |
| Source note | uspto-grants-2011_11 |