HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 66925065, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 3-Pyridinylboronic acid | HCID 2734378 | — |
| Reactant | HCID 66924849 | HCID 66924849 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Product | HCID 66925065 | HCID 66925065 | 63.4% |
Reaction Steps
Using tert-butyl {[5-bromo-1-(2-cyanophenyl)sulfonyl-1H-pyrrol-3-yl]methyl}methylcarbamate (296 mg), 3-pyridineboronic acid (162 mg), sodium carbonate (208 mg) and tetrakis(triphenylphosphine)palladium (38.2 mg), a procedure as in Reference Example 267 was performed to give the title compound as a white solid (yield 187 mg, 63%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08048909B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-d6ebc33456604a81ac90fab6642eaf64 |
| Source note | uspto-grants-2011_11 |