HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 57522379, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Thiophene-3-sulfonyl Chloride | HCID 2776378 | — |
| Reactant | Tert-butyl methyl[(5-phenyl-1H-pyrrol-3-YL)methyl]carbamate | HCID 57522146 | — |
| Product | HCID 57522379 | HCID 57522379 | 35.4% |
Reaction Steps
Using tert-butyl methyl[(5-phenyl-1H-pyrrol-3-yl)methyl]carbamate (250 mg), sodium hydride (60% in oil, 140 mg) and thiophene-3-sulfonyl chloride (340 mg), a procedure as in Example 36 was performed to give the title compound as pale-purple crystals (yield 114 mg, 35%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08048909B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-21dbe10ffb0b4e43bfe80e229d45f1c6 |
| Source note | uspto-grants-2011_11 |