HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-(2-benzyloxybenzyl)benzoate → Methyl 4-(2-hydroxybenzyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-(2-benzyloxybenzyl)benzoate | HCID 21909320 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 4-(2-hydroxybenzyl)benzoate | HCID 21909287 | 96% |
Reaction Steps
To a solution of 4-(2-benzyloxybenzyl)benzoic acid methyl ester (2.39 g, 7.19 mmol) in methanol (70 mL), a 20% palladium hydroxide catalyst (239 mg) was added. The mixture was stirred under a hydrogen atmosphere for five hours, and then the catalyst was filtered off. The solvent was distilled under reduced pressure to obtain the title compound (1.16 g, 96%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08048897B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-6b2966af80074a14aeeabd30cdb7dd1d |
| Source note | uspto-grants-2011_11 |