Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 554533Generated: October 29, 2026

Methyl 4-(2-benzyloxybenzyl)benzoate → Methyl 4-(2-hydroxybenzyl)benzoate

https://huagongshe.com/reaction/554533

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(2-benzyloxybenzyl)benzoateHCID 21909320—
CatalystPalladium hydroxideHCID 9942167—
SolventMethanolHCID 887—
ProductMethyl 4-(2-hydroxybenzyl)benzoateHCID 2190928796%

Reaction Steps

To a solution of 4-(2-benzyloxybenzyl)benzoic acid methyl ester (2.39 g, 7.19 mmol) in methanol (70 mL), a 20% palladium hydroxide catalyst (239 mg) was added. The mixture was stirred under a hydrogen atmosphere for five hours, and then the catalyst was filtered off. The solvent was distilled under reduced pressure to obtain the title compound (1.16 g, 96%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08048897B2
Source datasetuspto-grants-2011_11
ORD IDord-6b2966af80074a14aeeabd30cdb7dd1d
Source noteuspto-grants-2011_11