Hydrochloric Acid → HCID 53786553, compound

Participants

Reaction Steps

To a solution of (2-benzyloxyphenyl)-(4-tert-butylphenyl)methanol (2.17 g, 6.26 mmol) in methanol (27 mL), a 20% palladium hydroxide catalyst (217 mg) was added and furthermore 2N—HCl (0.52 mL) was added thereto. The mixture was stirred under a hydrogen atmosphere for 24 hours, and then the catalyst was filtered off. The solvent was distilled and the obtained residue was purified by silica gel column chromatography [developing solution=ethyl acetate:n-hexane (1:10)] to obtain the title compound (1.3 g, 86%).

Provenance & Evidence