Hydrochloric Acid → HCID 67460490, compound

Participants

Reaction Steps

To a solution of (2-benzyloxy-6-methylphenyl)-(4-methoxyphenyl)-methanol (2.39 g, 7.15 mmol) in methanol (50 mL), a 20% palladium hydroxide catalyst (0.36 g) was added and furthermore 36% HCl (0.36 mL) was added thereto. The mixture was stirred under a hydrogen atmosphere for 11 hours, and then the catalyst was filtered off. The solvent was distilled under reduced pressure and the obtained residue was purified by silica gel column chromatography [developing solution=ethyl acetate:n-hexane (1:5)] to obtain the title compound (1.40 g, 86%).

Provenance & Evidence