HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylamine → [2-Chloro-5-(2-ethylaminomethyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylamine | HCID 6341 | — |
| Reactant | [2-Chloro-5-(2-formyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester | HCID 86640533 | — |
| Product | [2-Chloro-5-(2-ethylaminomethyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester | HCID 86640535 | — |
Reaction Steps
[2-Chloro-5-(2-formyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester and ethylamine (2M in THF) were reacted as described in Example 3, Step 3 to provide [2-chloro-5-(2-ethylaminomethyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08049015B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-302a785e85bd484596942fbd90841d7d |
| Source note | uspto-grants-2011_11 |