Ethylamine → HCID 67212291, compound

HRID 554623Notes

Reaction equation

HRID 554623 reaction equation
[CH3:1][O:2][C:3](=[O:23])[CH2:4][C:5]1[CH:6]=[N:7][CH:8]=[C:9]([C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[CH:13][C:12]=2[CH:21]=O)[CH:10]=1.[CH2:24]([NH2:26])[CH3:25]>>[CH3:1][O:2][C:3](=[O:23])[CH2:4][C:5]1[CH:6]=[N:7][CH:8]=[C:9]([C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:18])([F:20])[F:19])=[CH:13][C:12]=2[CH2:21][NH:26][CH2:24][CH3:25])[CH:10]=1

Participants

3

Reactant 2

HCID 6341EthylamineHCID 86640539[5-(2-Formyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid methyl ester

Product 1

HCID 67212291HCID 67212291, compound

Procedure

[5-(2-Formyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid methyl ester and ethylamine (2M in MeOH) were reacted as described in Example 8, Step 1 to provide [5(2-ethylaminomethyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid methyl ester.

Sources & evidence

ORD record
ord-d9594d5ac7344bcdbef3f7dd2e9da3ee
Source dataset
uspto-grants-2011_11
Patent number
US08049015B2

Reaction notes

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