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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 554624Generated: October 31, 2026

Benzyl chloroformate → (5-{2-[(N-benzyloxycarbonyl-N-ethyl-amino)-methyl]-4-trifluoromethyl-phenyl}-pyridin-3-yl)-acetic acid methyl ester

https://huagongshe.com/reaction/554624

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl chloroformateHCID 10387—
ReactantHCID 67212291HCID 67212291—
Product(5-{2-[(N-benzyloxycarbonyl-N-ethyl-amino)-methyl]-4-trifluoromethyl-phenyl}-pyridin-3-yl)-acetic acid methyl esterHCID 67212363—

Reaction Steps

[5-(2-Ethylaminomethyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid methyl ester and benzyl chloroformate were reacted as described in Example 11, Step 2 to provide (5-{2-[(N-benzyloxycarbonyl-N-ethyl-amino)-methyl]-4-trifluoromethyl-phenyl}-pyridin-3-yl)-acetic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08049015B2
Source datasetuspto-grants-2011_11
ORD IDord-b92972b9ea20495c965f76bd146f4873
Source noteuspto-grants-2011_11