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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 554628Generated: October 30, 2026

Phenylacetic Acid → (5-{2-[(N-ethyl-N-phenylacetyl-amino)-methyl]-4-trifluoromethyl-phenyl}-pyridin-3-yl)-acetic acid methyl ester

https://huagongshe.com/reaction/554628

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylacetic AcidHCID 999—
ReactantHCID 131729246HCID 131729246—
Product(5-{2-[(N-ethyl-N-phenylacetyl-amino)-methyl]-4-trifluoromethyl-phenyl}-pyridin-3-yl)-acetic acid methyl esterHCID 67212478—

Reaction Steps

[5-(2-Ethylaminomethyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid methyl ester, dihydrochloride and phenyl-acetic acid were reacted as described in Example 8, Step 6 to provide (5-{2-[(N-ethyl-N-phenylacetyl-amino)-methyl]-4-trifluoromethyl-phenyl}-pyridin-3-yl)-acetic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08049015B2
Source datasetuspto-grants-2011_11
ORD IDord-c795199a4a964080b533112c6e3a34aa
Source noteuspto-grants-2011_11