Ethyl 2-(5-bromopyridin-3-yl)acetate → (5-{2-[(N-Acetyl-N-benzyl-amino)-methyl]-4-trifluoromethyl-phenyl}-pyridin-3-yl)-acetic acid

Participants

Reaction Steps

N-Benzyl-N-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-acetamide and (5-bromo-pyridin-3-yl)-acetic acid ethyl ester were reacted as described in Example 17, Step 4 and the product was hydrolyzed to the acid as described in Example 17, Step 5.

Provenance & Evidence