HCID 86640540, compound → HCID 45138776, compound

HRID 554635Notes

Reaction equation

HRID 554635 reaction equation
C(OC(=O)CC1C=NC(Cl)=C(C2C=CC(C(F)(F)F)=CC=2CN(C(=O)C)CC2C=CC=CC=2)C=1)C.C([O:38][C:39](=[O:70])[CH2:40][C:41]1[C:42]([Cl:69])=[N:43][CH:44]=[C:45]([C:47]2[CH:52]=[CH:51][C:50]([C:53]([F:56])([F:55])[F:54])=[CH:49][C:48]=2[CH2:57][N:58]([C:66](=[O:68])[CH3:67])[CH2:59][C:60]2[CH:65]=[CH:64][CH:63]=[CH:62][CH:61]=2)[CH:46]=1)C>>[C:66]([N:58]([CH2:57][C:48]1[CH:49]=[C:50]([C:53]([F:55])([F:54])[F:56])[CH:51]=[CH:52][C:47]=1[C:45]1[CH:46]=[C:41]([CH2:40][C:39]([OH:70])=[O:38])[C:42]([Cl:69])=[N:43][CH:44]=1)[CH2:59][C:60]1[CH:65]=[CH:64][CH:63]=[CH:62][CH:61]=1)(=[O:68])[CH3:67]

Participants

3

Reactant 2

HCID 86640540HCID 86640540, compoundHCID 86640541HCID 86640541, compound

Product 1

HCID 45138776HCID 45138776, compound

Procedure

Prepared according to the procedure described in Example 17, Step 5, using the following starting material: a mixture of (5-{2-[(N-acetyl-N-benzyl-amino)-methyl]-4-trifluoromethyl-phenyl}-6-chloro-pyridin-3-yl)-acetic acid ethyl ester and (5-{2-[(N-acetyl-N-benzyl-amino)-methyl]-4-trifluoromethyl-phenyl}-2-chloro-pyridin-3-yl)-acetic acid ethyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-7fd66b28f7be4f749e9533f975d04cf0
Source dataset
uspto-grants-2011_11
Patent number
US08049015B2

Reaction notes

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