HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 5-bromo-6-methoxy-3-pyridineacetate → (5-{2-[(N-Acetyl-N-benzyl-amino)-methyl]-4-trifluoromethyl-phenyl}-6-methoxy-pyridin-3-yl)-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 5-bromo-6-methoxy-3-pyridineacetate | HCID 58539686 | — |
| Reactant | N-Benzyl-N-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-acetamide | HCID 67212483 | — |
| Product | (5-{2-[(N-Acetyl-N-benzyl-amino)-methyl]-4-trifluoromethyl-phenyl}-6-methoxy-pyridin-3-yl)-acetic acid | HCID 45138921 | — |
Reaction Steps
Prepared according to the procedure described in Example 17, Step 4 and Step 5, using the following starting materials: N-benzyl-N-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-acetamide and (5-bromo-6-methoxy-pyridin-3-yl)-acetic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08049015B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-0b919cce3909450ca34d60a884a3078f |
| Source note | uspto-grants-2011_11 |