2-Pyridineacetic acid, hydrochloride (1:1) → [5-(2-{[N-ethyl-N-(2-pyridin-2-yl-acetyl)-amino]-methyl}-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester

Beteiligte Stoffe

Reaktionsschritte

[5-(2-ethylaminomethyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester and 2-pyridylacetic acid hydrochloride were reacted as described in Example 8, Step 6 to provide [5-(2-{[N-ethyl-N-(2-pyridin-2-yl-acetyl)-amino]-methyl}-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester. The ester was hydrolyzed to the acid as described in Example 30, Step 2.

Herkunft & Nachweise