Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methoxyacetic Acid → [5-(2-{[N-ethyl-N-(2-methoxy-acetyl)-amino]-methyl}-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methoxyacetic Acid | HCID 12251 | — |
| 반응물 | [5-(2-Ethylaminomethyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester | HCID 67212445 | — |
| 생성물 | [5-(2-{[N-ethyl-N-(2-methoxy-acetyl)-amino]-methyl}-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester | HCID 67212302 | — |
반응 단계
[5-(2-Ethylaminomethyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester and methoxyacetic acid were reacted as described in Example 8, Step 6 to provide [5-(2-{[N-ethyl-N-(2-methoxy-acetyl)-amino]-methyl}-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid ethyl ester. The ester was hydrolyzed to the acid as described in Example 30, Step 2.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08049015B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-717ba0c62cd348548ec381fd52d68c72 |
| 출처 메모 | uspto-grants-2011_11 |