Methylamine → 6-(5-Chloro-2-methoxybenzyl)-n-{(1r)-1-[(methylamino)carbonyl]propyl}-3,7-dioxo-1,4-diazepan-1-carboxamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Methylamine	HCID 6329	—
Edukt	Glycine tert-butyl ester hydrochloride	HCID 2725036	—
Edukt	Tert-butyl {[2-({[6-(5-chloro-2-methoxybenzyl)-3,7-dioxo-1,4-diazepan-1-yl]carbonyl}amino)butanoyl]amino}acetate	HCID 76588771	—
Produkt	6-(5-Chloro-2-methoxybenzyl)-n-{(1r)-1-[(methylamino)carbonyl]propyl}-3,7-dioxo-1,4-diazepan-1-carboxamide	HCID 57671011	—

Reaktionsschritte

Instead of the starting material compound of Example 220, that is, glycine tert-butyl ester hydrochloride, a methylamine 30% ethanol solution was used for the similar procedure as in Example 220 to obtain the title compound.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08049006B2
Quelldatensatz	uspto-grants-2011_11
ORD ID	ord-55ecc903678442df8262f08f14ba4b4a
Quellennotiz	uspto-grants-2011_11