4-Pentylphenyl 3-methyl-4-nitrobenzoate → 4-Pentylphenyl 4-amino-3-methylbenzoate

Participants

Reaction Steps

16.2 g of 4-pentylphenyl 3-methyl-4-nitrobenzoate (49.5 mM) were dissolved in 250 ml of ethyl acetate and 1.5 g of Pd/C (10%) were added. This mixture was hydrogenated at normal pressure. When the theoretical amount of hydrogen was consumed, it was filtered through a pad of celite filter aid and evaporated to dryness to give 14.5 g (49.0 mM, 98%) of 4-pentylphenyl 4-amino-3-methylbenzoate as beige crystals.

Provenance & Evidence