反应详情

A mixture of 100 g of 2,2-adamantane dimethanol, 48.2 g of methacrylic acid, 20 g of toluene, 25 g of acidic ion-exchange resin Amberlist-15, and 0.1 g of 2,2′-methylenebis(6-t-butyl-p-cresol) was heated at 120° C. for 6 hours while the water being formed was azeotroped off. After the reaction mixture resumed room temperature, it was filtered through Celite. The filtrate was concentrated in vacuum. 300 g of hexane was added to the concentrate for recrystallization. The crystals were recovered and dried in vacuum, obtaining 45.0 g (yield 33%) of the target compound. The spectral data of this compound were identical with those of the product in Synthesis Example 1-2.

1. customformed
2. customwas azeotroped off
3. customresumed room temperature
4. filtrationit was filtered through Celite
5. concentrationThe filtrate was concentrated in vacuum
6. addition300 g of hexane was added to the
7. concentrationconcentrate for recrystallization
8. customThe crystals were recovered
9. customdried in vacuum