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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 555252Generated: October 30, 2026

4-Bromobenzaldehyde → HCID 43338295, compound

https://huagongshe.com/reaction/555252

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-BromobenzaldehydeHCID 70741—
Reactant5-Bromo-1,2,3-trimethoxybenzeneHCID 75885—
ReactantCornforth reagentHCID 2724130—
ReactantMagnesiumHCID 5462224—
ProductHCID 43338295HCID 43338295—

Reaction Steps

First, magnesium was added to 1-bromo-3,4,5-trimethoxybenzene as a starting material, as shown in Reaction 6, and then 4-bromobenzaldehyde was added thereto to obtain a compound. Thus obtained compound was oxidized using PDC to obtain a Compound 21 derivative [(4-bromophenyl)(3,4,5-trimethoxyphenyl)methanone]. Using thus obtained compound as a starting material aminothiazole was introduced in the same manner as in the synthesis of Compound 516 to obtain Compound 571 in a form of a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08053439B2
Source datasetuspto-grants-2011_11
ORD IDord-1862126e9fed49229808938514d23508
Source noteuspto-grants-2011_11