HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbazole → HCID 9866219, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbazole | HCID 6854 | — |
| Reactant | tert-Butyl 4-[(oxiran-2-yl)methyl]piperazine-1-carboxylate | HCID 15491146 | — |
| Product | HCID 9866219 | HCID 9866219 | 82% |
Reaction Steps
The same method as employed in the preparation of Example 1 but starting from 9H-carbazole and (±)-4-oxiranylmethyl-piperazine-1-carboxylic acid tert-butyl ester (prepared according to the procedure of Toldy, L. et al., WO 97/14685) gives after flash chromatography the title compound as a pale yellow foam in a 82% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08053436B1 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-e2409b6a9a36425e8c4b6d8fd904a239 |
| Source note | uspto-grants-2011_11 |