HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 9915979, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3,6-Dibromocarbazole | HCID 274874 | — |
| Reactant | tert-Butyl 4-[(oxiran-2-yl)methyl]piperazine-1-carboxylate | HCID 15491146 | — |
| Product | HCID 9915979 | HCID 9915979 | 72% |
Reaction Steps
The same method as employed in the preparation of Example 1 but starting from 3,6-dibromo-9H-carbazole, (±)-4-oxiranylmethyl-piperazine-1-carboxylic acid tert-butyl ester and sodium hydride gives after flash chromatography the title compound as a white foam in a 72% yield. M.p: 90-95° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08053436B1 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-3e5a6e250c4f4bd89c2670f7eb3edd35 |
| Source note | uspto-grants-2011_11 |