Hydrochloric Acid → HCID 45117461, compound

Participants

Reaction Steps

1-[6-(N-tert-Butoxycarbonylamino)-1-hexyl]-1,2-dihydroquinoline-2-one (480 mg) was treated with a large excess of hydrogen chloride in dietyl ether with stirring for 1 hour at room temperature. The crystalline product was isolated by filtration and redissolved in water whereafter the solution was made strongly alkaline with sodium hydroxide and extracted twice with chloroform. The organic phase was dried over potassium carbonate, filtered and evaporated to yield the title compound as a colourless oil.

Provenance & Evidence