Dabco → HCID 10708760, compound

Participants

Reaction Steps

4-(Methoxycarbonyl)benzaldehyde (3.3 g, 20 mM), t-butylacrylate (3.5 ml, 24 mM) and 1,4-diazabicyclo[2,2,2]octane (449 mg, 4 mM) were mixed and stirred in a vessel at room temperature for 5 days. The resulting mixture was extracted with diethyl ether. The organic layer was separated, washed with 2N hydrochloric acid, water, and sodium bicarbonate in order, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The residue thus obtained was subjected to a silica gel column chromatography, to obtain 4.2 g of the title compound as a white solid (yield 73%).

Provenance & Evidence