Trifluoroacetic acid → HCID 24899788, compound

Participants

Reaction Steps

The compound of formula 4d (103 mg, 0.19 mmol) obtained in Example 4-4 was dissolved in dichloromethane (1.5 ml), and trifluoroacetic acid (0.07 ml, 0.95 mmol) was added dropwise thereto at room temperature. The resulting mixture was reacted at room temperature for 8 hours. After the completion of reaction, the reaction solution was concentrated under reduced pressure, and the residue thus obtained was purified by a preparative HPLC, to obtain 37 mg of the title compound as pale orange foam, which was used in the subsequent analysis.

Provenance & Evidence