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HRID555473

反应详情

EQUATION

反应方程式

HRID 555473 的结构方程式

REACTANTS

反应物

3
反应SMILES：COc1cc(C=O)cc(OC)c1
HCID81747

3,5-Dimethoxybenzaldehyde

C9H10O3

反应SMILES：COc1cc(N)c(C(N)=O)c(OC)c1
HCID20349016

2-Amino-4,6-dimethoxybenzamide

C9H12N2O3

反应SMILES：COc1cc(OC)c2c(=O)[nH]c(-c3ccccn3)nc2c1
HCID136037998

未命名化合物

PRODUCTS

产物

1
反应SMILES：COc1cc(OC)cc(-c2nc3cc(OC)cc(OC)c3c(=O)[nH]2)c1
HCID135907865

未命名化合物

收率 46%

PROCEDURE

实验过程

2-(3,5-dimethoxyphenyl)-5,7-dimethoxyquinazolin-4(3H)-one was synthesized from 2-amino-4,6-dimethoxybenzamide and 3,5-dimethoxybenzaldehyde, using the method described for 5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-one. 2-(3,5-dimethoxyphenyl)-5,7-dimethoxyquinazolin-4(3H)-one (120 mg, 46%) was isolated as a yellow solid. Selected data: MS (m/z): 343.05; MP 270-272° C.